SCHEMBL5330378

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5323653	0.91	CYP2C19 (0.50)	CYP2C19EPHX1TBXAS1CYP2D6CYP1A2
	SCHEMBL1061595	0.89	EPHX1 (0.58)	CYP2C19EPHX1TBXAS1CYP2D6CYP1A2
	SCHEMBL2878605	0.87	CYP2C19 (0.50)	CYP2C19TBXAS1CYP2D6CYP1A2SMN1; SMN2
	SCHEMBL14360139	0.84	TBXAS1 (0.60)	CYP2C19EPHX1TBXAS1CYP2D6CPN1
	SCHEMBL1065526	0.84	EPHX1 (0.56)	CYP2C19EPHX1TBXAS1CYP2D6CYP1A2
	SCHEMBL22612300	0.84	CYP2C19 (0.47)	CYP2C19EPHX1TBXAS1CYP2D6CPN1
	SCHEMBL3781893	0.83	HRH1 (0.59)	CYP2C19EPHX1TBXAS1CYP2D6CPN1
	SCHEMBL4219820	0.82	HRH1 (0.57)	CYP2C19TBXAS1CYP2D6CYP1A2PKM
	Ammonia Solution, Strong SCHEMBL28556745	0.82	TBXAS1 (0.59)	CYP2C19EPHX1TBXAS1CYP2D6CPN1
	Ammonia Solution, Strong SCHEMBL28562956	0.82	TBXAS1 (0.59)	CYP2C19EPHX1TBXAS1CYP2D6CPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.