Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775058 | 0.75 | TSHR (0.48) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL776890 | 0.75 | TSHR (0.48) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL3956655 | 0.73 | TSHR (0.46) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL1145685 | 0.72 | KMT2A (0.42) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL23713651 | 0.71 | TSHR (0.44) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL4976471 | 0.71 | TSHR (0.50) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL8813043 | 0.71 | TSHR (0.44) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL775059 | 0.71 | TSHR (0.44) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL9188707 | 0.71 | TSHR (0.44) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL7963041 | 0.70 | SLC6A3 (0.56) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1090615-C | Nα-2- (4-nitrophenylsulfonyl) ethoxycarbonyl amino acid | HYUNDAI PHARMACEUTICAL INDUSTR (KR) | 2002-09-11 | — | — | CN | claimed |
| US-6265590-B1 | NEW PROTECTED AMINO ACID DERIVATIVES USEFUL FOR PEPTIDE SYNTHESIS | HYUNDAI PHARM, IND. CO., LTD. (KR) | 2001-07-24 | — | — | US | claimed |
| CN-1234793-A | N 'alpha'-2-(4-nitrophenylsulfonyl) ethyoxycarbonyl-amino acids | HYUNDAI PHARMACEUTICAL INDUSTR (KR) | 1999-11-10 | — | — | CN | claimed |
| EP-0934260-A1 | N ALPHA-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | Hyundai Pharm. Ind. Co., Ltd. (KR) | 1999-08-11 | — | — | EP | claimed |
| WO-1998017638-A1 | Nα-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | HYUNDAI PHARM. IND. CO., LTD. (KR) | 1998-04-30 | — | — | WO | claimed |
| WO-2007007054-A1 | PHTHALAMIDES, SUCCINIMIDES AND RELATED COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2007-01-18 | — | — | WO | disclosed |
| CN-1090615-C | Nα-2- (4-nitrophenylsulfonyl) ethoxycarbonyl amino acid | HYUNDAI PHARMACEUTICAL INDUSTR (KR) | 2002-09-11 | — | — | CN | disclosed |
| US-6265590-B1 | NEW PROTECTED AMINO ACID DERIVATIVES USEFUL FOR PEPTIDE SYNTHESIS | HYUNDAI PHARM, IND. CO., LTD. (KR) | 2001-07-24 | — | — | US | disclosed |
| CN-1234793-A | N 'alpha'-2-(4-nitrophenylsulfonyl) ethyoxycarbonyl-amino acids | HYUNDAI PHARMACEUTICAL INDUSTR (KR) | 1999-11-10 | — | — | CN | disclosed |
| EP-0934260-A1 | N ALPHA-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | Hyundai Pharm. Ind. Co., Ltd. (KR) | 1999-08-11 | — | — | EP | disclosed |
| EP-0934260-A1 | N ALPHA-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | Hyundai Pharm. Ind. Co., Ltd. (KR) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017638-A1 | Nα-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | HYUNDAI PHARM. IND. CO., LTD. (KR) | 1998-04-30 | — | — | WO | disclosed |
| WO-1998017638-A1 | Nα-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | HYUNDAI PHARM. IND. CO., LTD. (KR) | 1998-04-30 | — | — | WO | disclosed |