Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.78 |
| ▸ | MAPT | P10636 | 2/20 | 0.78 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.78 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329826 | 0.83 | KDM4E (0.68) | KDM4EMAPTSAE1UBA2POLB | |
| SCHEMBL5329981 | 0.81 | ALDH1A1 (0.60) | KDM4EMAPTSAE1UBA2POLB | |
| SCHEMBL5332412 | 0.81 | KDM4E (0.66) | KDM4EMAPTSAE1UBA2POLB | |
| SCHEMBL5332362 | 0.81 | KDM4E (0.66) | KDM4EMAPTSAE1UBA2POLB | |
| SCHEMBL5328894 | 0.78 | KDM4E (0.81) | KDM4EMAPTSAE1UBA2POLB | |
| SCHEMBL5361482 | 0.77 | KDM4E (0.61) | KDM4EMAPTSAE1UBA2POLB | |
| SCHEMBL5326925 | 0.77 | KDM4E (0.60) | KDM4EMAPTSAE1UBA2POLB | |
| SCHEMBL5325065 | 0.77 | KDM4E (0.60) | KDM4EMAPTSAE1UBA2POLB | |
| SCHEMBL14346980 | 0.77 | PTGDR2 (1.00) | KDM4EMAPTSAE1UBA2POLB | |
| SCHEMBL5325062 | 0.76 | KDM4E (0.59) | KDM4EMAPTSAE1UBA2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | claimed |