Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.53 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333711 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4EHSD17B10RAB9A | |
| SCHEMBL5330735 | 0.81 | KDM4E (0.78) | ALDH1A1HPGDKDM4EHSD17B10RAB9A | |
| SCHEMBL5325066 | 0.81 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EHSD17B10RAB9A | |
| SCHEMBL5332450 | 0.81 | ALDH1A1 (0.78) | ALDH1A1HPGDKDM4EHSD17B10RAB9A | |
| SCHEMBL5326900 | 0.76 | ALDH1A1 (0.60) | ALDH1A1HPGDKDM4EHSD17B10RAB9A | |
| SCHEMBL30227915 | 0.71 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4EHSD17B10RAB9A | |
| SCHEMBL27928272 | 0.69 | ERAP1 (0.64) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL5085543 | 0.68 | ERAP1 (0.63) | ALDH1A1HPGDKDM4EHSD17B10RAB9A | |
| SCHEMBL658050 | 0.67 | TSHR (0.54) | ALDH1A1HPGDKDM4EHSD17B10RAB9A | |
| SCHEMBL27737319 | 0.64 | KMT2A (0.57) | ALDH1A1HPGDPOLBKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | claimed |