Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.62 |
| ▸ | LTA4H | P09960 | 5/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | BAX | Q07812 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24413619 | 0.98 | ESR1 (0.59) | ESR1MEN1KMT2AESR2LTA4H | |
| SCHEMBL24413564 | 0.93 | ESR1 (0.54) | ESR1MEN1KMT2AESR2LTA4H | |
| SCHEMBL18888382 | 0.86 | ESR1 (0.46) | ESR1MEN1KMT2AESR2LTA4H | |
| SCHEMBL8840891 | 0.84 | MEN1 (0.77) | ESR1MEN1KMT2AESR2LTA4H | |
| SCHEMBL249169 | 0.78 | ESR2 (1.00) | ESR1MEN1KMT2AESR2LTA4H | |
| SCHEMBL18198 | 0.78 | ESR2 (1.00) | ESR1MEN1KMT2AESR2LTA4H | |
| SCHEMBL7811939 | 0.78 | ESR2 (1.00) | ESR1MEN1KMT2AESR2LTA4H | |
| SCHEMBL3175106 | 0.78 | ESR2 (1.00) | ESR1MEN1KMT2AESR2LTA4H | |
| SCHEMBL11572569 | 0.78 | MEN1 (0.42) | ESR1MEN1KMT2AESR2LTA4H | |
| SCHEMBL522433 | 0.77 | ESR1 (0.74) | ESR1MEN1KMT2AESR2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |