SCHEMBL24413619

SCHEMBL24413619

Oc1ccc(Oc2c(F)c(F)c(F)c(F)c2F)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
ESR2 Q92731 1/20 0.59
HSD17B10 Q99714 1/20 0.52
LTA4H P09960 5/20 0.50
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
PARP10 Q53GL7 1/20 0.42
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA13 Q8N1Q1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5330786 0.98 ESR1 (0.62) ESR1MEN1KMT2AESR2HSD17B10
SCHEMBL24413564 0.91 ESR1 (0.54) ESR1MEN1KMT2AESR2HSD17B10
SCHEMBL18888382 0.88 ESR1 (0.46) ESR1MEN1KMT2AESR2HSD17B10
SCHEMBL8840891 0.82 MEN1 (0.77) ESR1MEN1KMT2AESR2HSD17B10
SCHEMBL5546635 0.76 HSD17B10 (0.47) MEN1KMT2AHSD17B10HPGDHTT
SCHEMBL18198 0.76 ESR2 (1.00) ESR1MEN1KMT2AESR2HSD17B10
SCHEMBL3175106 0.76 ESR2 (1.00) ESR1MEN1KMT2AESR2HSD17B10
SCHEMBL249169 0.76 ESR2 (1.00) ESR1MEN1KMT2AESR2HSD17B10
SCHEMBL7811939 0.76 ESR2 (1.00) ESR1MEN1KMT2AESR2HSD17B10
SCHEMBL11572569 0.76 MEN1 (0.42) ESR1MEN1KMT2AESR2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220146930-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220146930-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN RER1, FGFR1, NHERF1 ESR1 662/4885MEN1 2209/4885KMT2A 1914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.