Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329816 | 0.96 | HTR6 (0.41) | HTR6PTGDR2 | |
| SCHEMBL5420518 | 0.94 | PTGDR2 (0.45) | HTR6PTGDR2PTGDR | |
| SCHEMBL5325375 | 0.94 | HTR6 (0.50) | HTR6PTGDR2HDAC1HDAC2HDAC6 | |
| SCHEMBL5332081 | 0.92 | HTR6 (0.50) | HTR6PTGDR2HDAC1HDAC2HDAC6 | |
| SCHEMBL5327989 | 0.92 | HTR6 (0.52) | HTR6PTGDR2PTGDR | |
| SCHEMBL5328560 | 0.92 | HTR6 (0.48) | HTR6PTGDR2LMNAPTGDR | |
| SCHEMBL5331612 | 0.90 | HTR6 (0.56) | HTR6PTGDR2PTGDR | |
| SCHEMBL5327669 | 0.89 | HTR6 (0.45) | HTR6LMNAHDAC1HDAC2HDAC6 | |
| SCHEMBL5407869 | 0.84 | PTGDR2 (0.54) | HTR6PTGDR2LMNAPTGDR | |
| SCHEMBL5331698 | 0.84 | HTR6 (0.54) | HTR6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |