Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332248 | 0.93 | HTR6 (0.44) | HTR6GAAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5333172 | 0.89 | HTR6 (0.54) | HTR6GAAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5328013 | 0.89 | HTR6 (0.51) | HTR6GAAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5330895 | 0.88 | HTR6 (0.41) | HTR6GAAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5325375 | 0.86 | HTR6 (0.50) | HTR6 | |
| SCHEMBL5330802 | 0.84 | HTR6 (0.42) | HTR6GAA | |
| SCHEMBL5331697 | 0.83 | HTR6 (0.55) | HTR6GAAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5420518 | 0.83 | PTGDR2 (0.45) | HTR6 | |
| SCHEMBL5329816 | 0.83 | HTR6 (0.41) | HTR6MAPT | |
| SCHEMBL5333545 | 0.82 | HTR6 (0.41) | HTR6ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |