Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.47 |
| ▸ | CTSA | P10619 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5305245 | 0.86 | PLA2G7 (0.40) | PLA2G7CTSASCN1ASCN8ASCN5A | |
| SCHEMBL3034633 | 0.76 | PLA2G7 (0.43) | PLA2G7SCN1ASCN8ASCN5AMAPT | |
| SCHEMBL28151503 | 0.75 | MAPT (0.64) | PLA2G7GAAMAPTMEN1ALDH1A1 | |
| SCHEMBL2339694 | 0.74 | GCK (0.66) | SCN9AGRM4GCK | |
| SCHEMBL20256165 | 0.74 | SCN8A (0.50) | CTSASCN9ASCN1ASCN8ASCN5A | |
| SCHEMBL11896454 | 0.72 | PLA2G7 (0.51) | PLA2G7GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL3044208 | 0.72 | MAPT (0.52) | PLA2G7GAAMAPTKDM4EMEN1 | |
| SCHEMBL26662272 | 0.71 | MAPT (0.49) | PLA2G7GAAMAPTKDM4EMEN1 | |
| SCHEMBL722560 | 0.70 | RAB9A (0.59) | PLA2G7GAAMAPTMEN1ALDH1A1 | |
| SCHEMBL5329033 | 0.70 | PLA2G7 (0.49) | PLA2G7MAPTKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038387-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRUSES AND CANCER | YALE UNIVERSITY (US) | 2007-04-05 | — | — | WO | disclosed |