Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A3 | P40879 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.52 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.52 |
| ▸ | ACLY | P53396 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26434307 | 0.83 | ALDH1A1 (0.84) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5329826 | 0.82 | KDM4E (0.68) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5327916 | 0.80 | KDM4E (0.81) | SLC26A3ALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL6587019 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5361482 | 0.77 | KDM4E (0.61) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL5329160 | 0.76 | PTGDR2 (0.58) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5325062 | 0.76 | KDM4E (0.59) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL14346737 | 0.74 | KDM4E (0.57) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9834762 | 0.74 | LMNA (0.57) | ALDH1A1KDM4EKMT2AHPGDLMNA | |
| SCHEMBL5330434 | 0.74 | KDM4E (0.55) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |