Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 5/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335982 | 0.89 | CHRM2 (0.52) | FPR2CHRM2CHRM3CHRM1 | |
| SCHEMBL5331370 | 0.83 | NAMPT (0.42) | FPR2CHRM2CHRM3CHRM1NAMPT | |
| SCHEMBL2589812 | 0.75 | PTPN1 (0.44) | PTPN2PTPN1TMPRSS15 | |
| SCHEMBL29686968 | 0.73 | FPR2 (0.83) | FPR2CA12CA1CA9 | |
| Trifluoroacetic Acid SCHEMBL5331362 | 0.71 | NAMPT (0.46) | CHRM2CHRM3CHRM1NAMPTMLYCD | |
| SCHEMBL5335986 | 0.71 | CHRM2 (0.44) | CHRM2CHRM3CHRM1 | |
| SCHEMBL29687123 | 0.71 | FPR2 (0.81) | FPR2CA12CA1CA9 | |
| SCHEMBL10627281 | 0.70 | CA12 (0.53) | FPR2CA12CA1CA9 | |
| SCHEMBL5302819 | 0.68 | PTPN1 (0.50) | PTPN1 | |
| SCHEMBL29686903 | 0.68 | FPR2 (0.59) | FPR2CA12CA1CA9F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007018508-A1 | NOVEL M3 MUSCARINIC ACETYCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-02-15 | — | — | WO | disclosed |