Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.37 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.37 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.37 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.37 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.37 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5331362 | 0.88 | NAMPT (0.46) | NAMPTMLYCDCHRM2CHRM3CHRM1 | |
| SCHEMBL5335986 | 0.88 | CHRM2 (0.44) | CHRM2CHRM3CHRM1LMNAALDH1A1 | |
| SCHEMBL5331368 | 0.83 | FPR2 (0.46) | NAMPTMLYCDUSP30CHRM2CHRM3 | |
| Trifluoroacetic Acid SCHEMBL5335979 | 0.76 | CHRM2 (0.51) | CHRM2CHRM3CHRM1ERAP2LNPEP | |
| SCHEMBL5335982 | 0.72 | CHRM2 (0.52) | CHRM2CHRM3CHRM1FPR2 | |
| SCHEMBL2197917 | 0.72 | LTA4H (0.51) | — | |
| SCHEMBL3174534 | 0.71 | LTA4H (0.52) | MLYCDLMNAALDH1A1 | |
| SCHEMBL7445685 | 0.70 | PTPN1 (0.65) | CHRM2CHRM1LMNAALDH1A1CYP1A2 | |
| SCHEMBL5302819 | 0.70 | PTPN1 (0.50) | — | |
| SCHEMBL11363918 | 0.69 | OPRK1 (0.54) | ERAP2LNPEPERAP1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007018508-A1 | NOVEL M3 MUSCARINIC ACETYCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-02-15 | — | — | WO | disclosed |