Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 3/20 | 0.45 |
| ▸ | C1S | P09871 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12989543 | 0.79 | RAB9A (0.57) | RAB9AKDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL11466217 | 0.74 | KDM4E (0.86) | RAB9AKDM4ELMNASMN1; SMN2CYP19A1 | |
| SCHEMBL430121 | 0.70 | LTA4H (0.83) | RAB9AKDM4ELMNASMN1; SMN2CYP19A1 | |
| SCHEMBL28522859 | 0.70 | RAB9A (0.73) | RAB9AKDM4ELMNASMN1; SMN2CYP19A1 | |
| SCHEMBL3814593 | 0.69 | KDM4E (0.66) | RAB9AKDM4ELMNASMN1; SMN2CYP19A1 | |
| Bromide SCHEMBL8360642 | 0.69 | LTA4H (0.80) | RAB9AKDM4ELMNASMN1; SMN2CYP19A1 | |
| SCHEMBL3813712 | 0.69 | KDM4E (0.69) | RAB9AKDM4ELMNASMN1; SMN2CYP19A1 | |
| SCHEMBL15689161 | 0.68 | RAB9A (0.65) | RAB9AKDM4ELMNASMN1; SMN2CYP19A1 | |
| SCHEMBL4283884 | 0.68 | KDM4E (1.00) | RAB9AKDM4ELMNASMN1; SMN2CYP19A1 | |
| SCHEMBL4281217 | 0.68 | RAB9A (0.75) | RAB9AKDM4ELMNASMN1; SMN2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |