SCHEMBL5331532

SCHEMBL5331532

COc1ccc(CNC(=O)CCC(=O)O)cc1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.68
NPC1 O15118 2/20 0.66
TSHR P16473 1/20 0.65
MEN1 O00255 1/20 0.64
KMT2A Q03164 1/20 0.64
HTT P42858 2/20 0.64
PKM P14618 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
LMNA P02545 1/20 0.59
FFAR1 O14842 1/20 0.58
POLB P06746 1/20 0.58
RAB9A P51151 1/20 0.58
CNR1 P21554 1/20 0.58
GAA P10253 1/20 0.57
TRPV1 Q8NER1 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27909118 0.91 ALDH1A1 (0.72) ALDH1A1NPC1TSHRMEN1KMT2A
SCHEMBL27909130 0.91 ALDH1A1 (0.72) ALDH1A1NPC1TSHRMEN1KMT2A
SCHEMBL27892101 0.89 ALDH1A1 (0.71) ALDH1A1NPC1TSHRMEN1KMT2A
SCHEMBL13461105 0.87 MEN1 (0.64) ALDH1A1NPC1TSHRMEN1KMT2A
SCHEMBL7357569 0.87 MEN1 (0.64) ALDH1A1NPC1TSHRMEN1KMT2A
SCHEMBL5250976 0.87 NPC1 (0.69) ALDH1A1NPC1TSHRMEN1KMT2A
SCHEMBL4901981 0.86 MEN1 (0.63) ALDH1A1NPC1TSHRMEN1KMT2A
SCHEMBL12127405 0.85 CNR1 (0.67) ALDH1A1NPC1TSHRMEN1KMT2A
SCHEMBL14281354 0.84 TSHR (0.69) ALDH1A1NPC1TSHRMEN1KMT2A
SCHEMBL1484465 0.84 ALDH1A1 (0.63) ALDH1A1NPC1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102952105-A Mycophenolic acid derivative, preparation method thereof and application thereof SHANGHAI INST MATERIA MEDICA 2013-03-06 CN disclosed
WO-2007142431-A1 NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) 2007-12-13 WO disclosed