Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1544375 | 0.86 | ALDH1A1 (0.57) | ALDH1A1HSD17B10TSHRKDM4EUSP2 | |
| SCHEMBL6405168 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HSD17B10TSHRKDM4EUSP2 | |
| SCHEMBL19281531 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TSHRKDM4EUSP2 | |
| SCHEMBL1544956 | 0.80 | HSD17B10 (0.64) | ALDH1A1HSD17B10TSHRKDM4EUSP2 | |
| SCHEMBL1545353 | 0.80 | MAPT (0.41) | ALDH1A1HSD17B10TSHRKDM4EUSP2 | |
| SCHEMBL1545274 | 0.77 | TSHR (0.61) | ALDH1A1HSD17B10TSHRKDM4EUSP2 | |
| SCHEMBL1104378 | 0.77 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TSHRKDM4EUSP2 | |
| SCHEMBL5336422 | 0.74 | ALPL (0.71) | ALDH1A1HSD17B10TSHRKDM4EUSP2 | |
| SCHEMBL1544438 | 0.74 | MEN1 (0.47) | ALDH1A1TSHRKDM4ETP53SMN1; SMN2 | |
| SCHEMBL6403612 | 0.73 | ALDH1A1 (0.61) | ALDH1A1HSD17B10TSHRKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |