SCHEMBL5331701

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5331924	0.83	AURKA (0.61)	KDRAURKAKDM4EMEN1NPC1
	SCHEMBL5332443	0.81	KDR (0.59)	KDRAURKAKDM4EMEN1NPC1
	SCHEMBL5314912	0.80	KDR (1.00)	KDRAURKAKDM4EMEN1NPC1
	SCHEMBL5329803	0.78	KDR (0.77)	KDRAURKAKDM4EMEN1NPC1
	SCHEMBL3047766	0.75	CHEK1 (0.55)	KDRAURKAKDM4E
	Hydrochloric Acid SCHEMBL3050705	0.73	AURKA (0.48)	KDRAURKACDK1ROCK2
	SCHEMBL11691555	0.72	CA2 (0.52)	KDRAURKAKDM4EMEN1NPC1
	Hydrochloric Acid SCHEMBL3044267	0.72	CHEK1 (0.55)	KDRAURKA
	SCHEMBL3038071	0.72	AURKA (0.46)	KDRAURKAKDM4EMEN1MAPT
	SCHEMBL5330843	0.72	AURKA (0.67)	KDRAURKAKDM4EMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.