Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312683 | 0.77 | LCK (0.39) | BRAFKDRALDH1A1NQO2IKBKB | |
| SCHEMBL5309824 | 0.77 | TSHR (0.39) | KDM4EBRAFKDRALDH1A1SMN1; SMN2 | |
| SCHEMBL5316068 | 0.75 | BRAF (0.43) | BRAFKDRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL12482906 | 0.74 | TUBB4A (0.44) | KDM4EKDRALDH1A1TUBB4ATUBB | |
| SCHEMBL15514643 | 0.74 | TUBB4A (0.46) | KDM4EALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL15515591 | 0.73 | RXRA (0.47) | KDM4EALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL5312770 | 0.72 | MAPT (0.40) | KDM4EALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL12483800 | 0.72 | TUBB4A (0.44) | KDM4EALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL12482909 | 0.71 | SMN1; SMN2 (0.45) | KDM4EALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL15514326 | 0.71 | TUBB4A (0.43) | KDM4EALDH1A1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |