SCHEMBL996983

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14116546	0.82	MPL (0.55)	CBFBFEN1ALOX5APMPLTGFBR1
	SCHEMBL4730316	0.82	CBFB (0.50)	CBFBTGFBR1ALDH1A1KDM4EMEN1
	SCHEMBL28209756	0.82	CBFB (0.50)	CBFBFEN1ALOX5APTGFBR1F2
	SCHEMBL6301360	0.82	CBFB (0.50)	CBFBFEN1ALOX5APTGFBR1ALDH1A1
	SCHEMBL1206412	0.82	CBFB (0.50)	CBFBFEN1ALOX5APTGFBR1ALDH1A1
	SCHEMBL5331896	0.81	NPC1 (0.53)	CBFBTGFBR1ALDH1A1MEN1MAPT
	SCHEMBL11272726	0.81	ALOX5AP (0.50)	CBFBFEN1ALOX5APTGFBR1KDM4E
	SCHEMBL5990281	0.77	KDM1A (0.50)	CBFBTGFBR1F2F12ALDH1A1
	SCHEMBL4728125	0.77	CBFB (0.49)	CBFBTGFBR1KDM4EGAAGRM5
	SCHEMBL28163157	0.77	GRM5 (0.48)	CBFBFEN1ALOX5APTGFBR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.