Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23270712 | 0.98 | LMNA (0.52) | CYP3A4LMNAMEN1NR1I2CHRM2 | |
| Hydrochloric Acid SCHEMBL30306662 | 0.98 | CYP3A4 (0.49) | CYP3A4LMNAMEN1NR1I2CHRM2 | |
| SCHEMBL1003281 | 0.89 | HTT (0.46) | CYP3A4LMNAMEN1NR1I2CHRM2 | |
| SCHEMBL29217865 | 0.87 | MEN1 (0.43) | CYP3A4LMNAMEN1NR1I2CHRM2 | |
| SCHEMBL6680659 | 0.86 | ALDH1A1 (0.57) | CYP3A4LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL6680902 | 0.84 | ALDH1A1 (0.59) | LMNAMEN1KMT2AALDH1A1PRSS1 | |
| SCHEMBL28556526 | 0.84 | CYP3A4 (0.54) | CYP3A4LMNAMEN1NR1I2CHRM2 | |
| Potassium SCHEMBL30050002 | 0.84 | ALDH1A1 (0.56) | CYP3A4LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL8099853 | 0.84 | ALDH1A1 (0.46) | CYP3A4LMNAALDH1A1PRSS1PRSS2 | |
| SCHEMBL8093492 | 0.84 | ALDH1A1 (0.46) | CYP3A4LMNAALDH1A1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969937-A | BCL-2 inhibitors | 百济神州有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116969936-A | BCL-2 inhibitors | 百济神州有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116802179-A | BCL-2 inhibitors | 百济神州有限公司 | 2023-09-22 | — | — | CN | disclosed |
| WO-2007058960-A1 | SULFAMOYL BENZAMIDES AS CANNABINOID RECEPTOR MODULATORS | ADOLOR CORPORATION (US) | 2007-05-24 | — | — | WO | disclosed |