Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL6553065 | 1.00 | — | — | |
| Bicarbonate SCHEMBL1908229 | 1.00 | CA1 (0.55) | CA1CA9CA6CA5ACA5B | |
| Oxalic Acid SCHEMBL6254640 | 0.84 | CA1 (0.46) | CA1CA9CA6CA5ACA5B | |
| Acetic Acid SCHEMBL18063116 | 0.84 | — | — | |
| Carbamic Acid SCHEMBL5990476 | 0.84 | — | — | |
| Acetic Acid SCHEMBL10828286 | 0.81 | FFAR3 (0.50) | CA1CA9CA6CA5ACA5B | |
| Carbamic Acid SCHEMBL16013541 | 0.81 | ACHE (0.50) | CA1CA9CA6CA5ACA5B | |
| Bicarbonate SCHEMBL8020328 | 0.80 | — | — | |
| Bicarbonate SCHEMBL28201863 | 0.80 | — | — | |
| SCHEMBL6526159 | 0.78 | CA1 (0.40) | CA1CA9CA6CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007026949-A1 | EMULSION TYPE RESIN COMPOSITION | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |