Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL6553065 | 0.84 | — | — | |
| Oxalic Acid SCHEMBL28100093 | 0.84 | CA1 (0.46) | CA1CA9 | |
| Bicarbonate SCHEMBL5332176 | 0.84 | CA1 (0.55) | CA1CA6CA5ACA9CA5B | |
| Bicarbonate SCHEMBL1908229 | 0.84 | CA1 (0.55) | CA1CA6CA5ACA9CA5B | |
| Carbamic Acid SCHEMBL16013541 | 0.81 | ACHE (0.50) | CA1CA6CA5ACA9CA5B | |
| Acetic Acid SCHEMBL18063116 | 0.77 | — | — | |
| Carbamic Acid SCHEMBL5990476 | 0.77 | — | — | |
| Oxalic Acid SCHEMBL28540174 | 0.75 | LDHA (0.33) | CA1CA9 | |
| Acetic Acid SCHEMBL10828286 | 0.74 | FFAR3 (0.50) | CA1CA6CA5ACA9CA5B | |
| Bicarbonate SCHEMBL8020328 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100436540-C | Flame-retarded polyphenylene ether composition and method of making same | GEN ELECTRIC (US) | 2008-11-26 | — | — | CN | disclosed |
| CN-1827688-A | Flame-retarded polyphenylene ether composition and method of making same | GEN ELECTRIC (US) | 2006-09-06 | — | — | CN | disclosed |
| EP-1244737-B1 | FLAME-RETARDED POLYPHENYLENE ETHER COMPOSITION AND METHOD OF MAKING SAME | GEN ELECTRIC (US) | 2005-04-13 | — | — | EP | disclosed |
| US-6579926-B2 | To produce injection molded articles such as electronic components, including television internals such as deflection yokes; printer chassis and plastic pallets | GENERAL ELECTRIC COMPANY | 2003-06-17 | — | — | US | disclosed |
| CN-1423676-A | Flame-retardant polyphenylene ether composition and method for producing the same | GEN ELECTRIC (US) | 2003-06-11 | — | — | CN | disclosed |
| EP-1244737-A1 | FLAME-RETARDED POLYPHENYLENE ETHER COMPOSITION AND METHOD OF MAKING SAME | GENERAL ELECTRIC COMPANY (US) | 2002-10-02 | — | — | EP | disclosed |
| US-20020099124-A1 | FLAME-RETARDED POLYPHENYLENE ETHER COMPOSITION AND METHOD OF MAKING SAME | CITIBANK, N.A., AS COLLATERAL AGENT | 2002-07-25 | — | — | US | disclosed |
| WO-2002018485-A1 | FLAME-RETARDED POLYPHENYLENE ETHER COMPOSITION AND METHOD OF MAKING SAME | GENERAL ELECTRIC COMPANY (US) | 2002-03-07 | — | — | WO | disclosed |
| WO-2001036527-A1 | FLAME-RETARDED POLYPHENYLENE ETHER COMPOSITION AND METHOD OF MAKING SAME | GENERAL ELECTRIC COMPANY (US) | 2001-05-25 | — | — | WO | disclosed |
| US-5561199-A | CONTAINING POLYPHENYLENE ETHER, POLYARYLENE SULFIDE, POLYISOCYANATE; IMPACT STRENGTH | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1996-10-01 | — | — | US | disclosed |
| US-5449721-A | Thermoplastic resin compositions comprising polyphenylene ether, polyamide and fluorocarbon resins | SUMITOMO CHEMICAL CO., LTD. (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0542296-B1 | Resin compositions | SUMITOMO CHEMICAL CO (JP) | 1995-08-23 | — | — | EP | disclosed |
| US-5336713-A | Polyphenylene ether and a polyarylene sulfide; excellent welding property | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0570972-A1 | Polyphenylene ether polyarylene sulfide composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-24 | — | — | EP | disclosed |
| EP-0568039-A1 | Resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-03 | — | — | EP | disclosed |
| EP-0542296-A1 | Resin compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-19 | — | — | EP | disclosed |