Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 10/20 | 0.64 |
| ▸ | CA2 | P00918 | 10/20 | 0.64 |
| ▸ | CA9 | Q16790 | 10/20 | 0.64 |
| ▸ | CA12 | O43570 | 7/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30988938 | 0.89 | LMNA (0.60) | LMNAMAPK1ALDH1A1THRBTSHR | |
| SCHEMBL4957501 | 0.89 | LMNA (0.63) | LMNAMAPK1ALDH1A1THRBTSHR | |
| SCHEMBL4957507 | 0.89 | LMNA (0.63) | LMNAMAPK1ALDH1A1THRBTSHR | |
| SCHEMBL11881911 | 0.85 | LMNA (0.62) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Carnidazole SCHEMBL637201 | 0.84 | LMNA (0.60) | LMNAMAPK1ALDH1A1THRBTSHR | |
| SCHEMBL12369632 | 0.84 | CA1 (0.68) | LMNAMAPK1ALDH1A1THRBTSHR | |
| SCHEMBL12290289 | 0.83 | CA1 (0.55) | LMNAMAPK1ALDH1A1THRBTSHR | |
| SCHEMBL11871538 | 0.83 | MEN1 (0.55) | LMNAMAPK1ALDH1A1THRBTSHR | |
| SCHEMBL5309855 | 0.82 | LMNA (0.70) | LMNAMAPK1ALDH1A1THRBTSHR | |
| Metronidazole SCHEMBL3765189 | 0.82 | LMNA (0.91) | LMNAMAPK1ALDH1A1THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027878-A2 | 4-SUBSTITUTED 2-ARYLOXYPHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. (US) | 2007-03-08 | — | — | WO | claimed |