Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.60 |
| ▸ | DAO | P14920 | 2/20 | 0.60 |
| ▸ | NSD2 | O96028 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | LIG1 | P18858 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 4/20 | 0.48 |
| ▸ | CASP7 | P55210 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244367 | 1.00 | CES1 (0.60) | CES1DAONSD2BCHELIG1 | |
| SCHEMBL3088689 | 0.75 | DAO (1.00) | CES1DAONSD2BCHELIG1 | |
| SCHEMBL29417367 | 0.75 | CES1 (1.00) | CES1DAONSD2BCHELIG1 | |
| SCHEMBL29836255 | 0.75 | CES1 (0.60) | CES1DAONSD2BCHELIG1 | |
| SCHEMBL505703 | 0.75 | CES1 (0.60) | CES1DAONSD2BCHELIG1 | |
| SCHEMBL1247382 | 0.75 | CES1 (1.00) | CES1DAONSD2BCHELIG1 | |
| SCHEMBL29440762 | 0.75 | CES1 (0.60) | CES1DAONSD2BCHELIG1 | |
| SCHEMBL281604 | 0.75 | CES1 (0.60) | CES1DAONSD2BCHELIG1 | |
| SCHEMBL6845708 | 0.75 | CES1 (0.60) | CES1DAONSD2BCHELIG1 | |
| SCHEMBL29506270 | 0.75 | CES1 (0.60) | CES1DAONSD2BCHELIG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132280-A1 | ISATIN AND ITS DERIVATIVES FOR USE AS A MEDICAMENT | Szegedi Tudományegyetem (HU) | 2007-11-22 | — | — | WO | disclosed |