Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.60 |
| ▸ | DAO | P14920 | 2/20 | 0.60 |
| ▸ | BCHE | P06276 | 2/20 | 0.60 |
| ▸ | NSD2 | O96028 | 1/20 | 0.60 |
| ▸ | LIG1 | P18858 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | CASP2 | P42575 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 2/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29417367 | 0.75 | CES1 (1.00) | CES1DAOBCHENSD2LIG1 | |
| SCHEMBL3088689 | 0.75 | DAO (1.00) | CES1DAOBCHENSD2LIG1 | |
| SCHEMBL29836255 | 0.75 | CES1 (0.60) | CES1DAOBCHENSD2LIG1 | |
| SCHEMBL281604 | 0.75 | CES1 (0.60) | CES1DAOBCHENSD2LIG1 | |
| SCHEMBL505703 | 0.75 | CES1 (0.60) | CES1DAOBCHENSD2LIG1 | |
| SCHEMBL1247382 | 0.75 | CES1 (1.00) | CES1DAOBCHENSD2LIG1 | |
| SCHEMBL29440762 | 0.75 | CES1 (0.60) | CES1DAOBCHENSD2LIG1 | |
| SCHEMBL31244367 | 0.75 | CES1 (0.60) | CES1DAOBCHENSD2LIG1 | |
| SCHEMBL5332282 | 0.75 | CES1 (0.60) | CES1DAOBCHENSD2LIG1 | |
| SCHEMBL29506270 | 0.75 | CES1 (0.60) | CES1DAOBCHENSD2LIG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119704-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |
| EP-1812388-B1 | SULFONAMIDE PERI-SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE | DECODE GENETICS EHF (IS) | 2011-02-23 | — | — | EP | disclosed |