Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 13/20 | 0.43 |
| ▸ | CA1 | P00915 | 12/20 | 0.43 |
| ▸ | CA2 | P00918 | 12/20 | 0.43 |
| ▸ | CA12 | O43570 | 11/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467917 | 0.78 | CHRNA7 (0.44) | CHRNA7CA9CA1CA2CA12 | |
| SCHEMBL348164 | 0.75 | CA2 (0.44) | CHRNA7CA9CA1CA2CA12 | |
| SCHEMBL5312529 | 0.73 | PTGS2 (0.58) | CHRNA7CA9CA1CA2CA12 | |
| SCHEMBL347020 | 0.73 | PTGS2 (0.58) | CHRNA7CA9CA1CA2CA12 | |
| Apricoxib SCHEMBL346028 | 0.72 | CA1 (0.60) | CHRNA7CA9CA1CA2CA12 | |
| Apricoxib SCHEMBL3435344 | 0.72 | CA1 (0.60) | CHRNA7CA9CA1CA2CA12 | |
| SCHEMBL5316846 | 0.71 | PTGS2 (0.57) | CHRNA7CA9CA1CA2CA12 | |
| SCHEMBL5314130 | 0.71 | CA9 (0.62) | CHRNA7CA9CA1CA2CA12 | |
| SCHEMBL347479 | 0.70 | CA1 (0.59) | CHRNA7CA9CA1CA2CA12 | |
| SCHEMBL2463842 | 0.70 | CA1 (0.59) | CHRNA7CA9CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799823-B1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | DAIICHI SANKYO CO LTD (JP) | 2007-10-31 | — | — | EP | claimed |