Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | FLT1 | P17948 | 3/20 | 0.46 |
| ▸ | FLT4 | P35916 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452555 | 0.85 | ABL1 (0.58) | ABL1NR4A2FLT1FLT4KDR | |
| SCHEMBL21962924 | 0.84 | CA2 (0.61) | ABL1NR4A2FLT1FLT4KDR | |
| SCHEMBL11334105 | 0.78 | ABL1 (0.50) | ABL1NR4A2FLT1FLT4KDR | |
| SCHEMBL6100118 | 0.77 | ABL1 (0.70) | ABL1NR4A2FLT1FLT4KDR | |
| SCHEMBL4071409 | 0.76 | ABL1 (0.64) | ABL1NR4A2FLT1FLT4KDR | |
| SCHEMBL21962911 | 0.76 | ABL1 (0.48) | ABL1NR4A2FLT1FLT4KDR | |
| SCHEMBL8627703 | 0.76 | ABL1 (0.48) | ABL1NR4A2FLT1FLT4KDR | |
| SCHEMBL608814 | 0.75 | ABL1 (0.68) | ABL1NR4A2FLT1FLT4KDR | |
| SCHEMBL1017485 | 0.75 | ABL1 (0.54) | ABL1NR4A2FLT1FLT4KDR | |
| SCHEMBL17078006 | 0.75 | TRPV4 (0.56) | ABL1NR4A2FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144379-A1 | BICYCLIC COMPOUNDS USEFUL AS CATHEPSIN S INBHIBITORS | MEDIVIR AB (SE) | 2007-12-21 | — | — | WO | disclosed |