Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334794 | 0.88 | L3MBTL1 (0.43) | L3MBTL1TAAR1ALDH1A1KMT2ACHRNA7 | |
| SCHEMBL5333657 | 0.85 | L3MBTL1 (0.40) | L3MBTL1TAAR1ALDH1A1KMT2A | |
| SCHEMBL5314842 | 0.79 | L3MBTL1 (0.50) | L3MBTL1TAAR1CHRNA7 | |
| SCHEMBL3844985 | 0.73 | LMNA (0.46) | TAAR1ALDH1A1KMT2AGAA | |
| SCHEMBL3844987 | 0.73 | LMNA (0.46) | TAAR1ALDH1A1KMT2AGAA | |
| SCHEMBL2997114 | 0.72 | TAAR1 (0.45) | L3MBTL1TAAR1ALDH1A1CYP1A2CHRNA7 | |
| SCHEMBL2997110 | 0.72 | TAAR1 (0.45) | L3MBTL1TAAR1ALDH1A1CYP1A2CHRNA7 | |
| SCHEMBL25241870 | 0.71 | LMNA (0.43) | ALDH1A1CYP1A2KMT2A | |
| SCHEMBL5315145 | 0.70 | L3MBTL1 (0.38) | L3MBTL1TAAR1CYP1A2KMT2ACHRNA7 | |
| SCHEMBL14747110 | 0.66 | HTT (0.46) | L3MBTL1TAAR1ALDH1A1KMT2ACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067904-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-06-14 | — | — | WO | disclosed |