Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | BLM | P54132 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | GFER | P55789 | 2/20 | 0.58 |
| ▸ | ALPL | P05186 | 2/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.58 |
| ▸ | NQO2 | P16083 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31706727 | 0.80 | LCK (1.00) | LCKKDM4ERAB9APTGS2POLB | |
| SCHEMBL1824176 | 0.80 | LCK (1.00) | LCKKDM4ERAB9APTGS2POLB | |
| SCHEMBL1824175 | 0.80 | LCK (1.00) | LCKKDM4ERAB9APTGS2POLB | |
| SCHEMBL30631591 | 0.80 | LCK (1.00) | LCKKDM4ERAB9APTGS2POLB | |
| SCHEMBL14281154 | 0.79 | LCK (0.76) | LCKKDM4ERAB9APTGS2POLB | |
| SCHEMBL10335571 | 0.78 | LCK (0.94) | LCKKDM4ERAB9APTGS2POLB | |
| SCHEMBL11001027 | 0.77 | TSHR (0.52) | LCKKDM4ERAB9APTGS2ALDH1A1 | |
| Protocatechualdehyde SCHEMBL9512877 | 0.76 | KDM4E (1.00) | LCKKDM4ERAB9APTGS2POLB | |
| SCHEMBL17273589 | 0.76 | LCK (0.64) | LCKKDM4ERAB9APTGS2POLB | |
| SCHEMBL18995241 | 0.76 | LCK (0.64) | LCKKDM4ERAB9APTGS2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301279-B1 | ADSORPTION METHOD AND LIGANDS | CYTIVA BIOPROCESS R & D AB (SE) | 2020-10-28 | — | — | EP | disclosed |
| US-7214321-B2 | Adsorption method and ligands | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2007-05-08 | — | — | US | disclosed |
| US-20040256324-A1 | Adsorption method and ligands | CYTIVA BIOPROCESS R&D AB (SE) | 2004-12-23 | — | — | US | disclosed |
| EP-1301279-A2 | ADSORPTION METHOD AND LIGANDS | Amersham Pharmacia Biotech AB (SE) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002005959-A2 | ADSORPTION METHOD AND LIGANDS | AMERSHAM BIOSCIENCES AB (SE) | 2002-01-24 | — | — | WO | disclosed |