Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622273 | 0.83 | LCK (0.61) | TSHRHSD17B10CA2CA1BACE1 | |
| SCHEMBL9622274 | 0.83 | LCK (0.61) | TSHRHSD17B10CA2CA1BACE1 | |
| SCHEMBL131757 | 0.80 | ALDH1A1 (0.58) | TSHRHSD17B10KMT2AALDH1A1GUSB | |
| SCHEMBL7411287 | 0.79 | CA2 (0.52) | TSHRHSD17B10CA2CA1BACE1 | |
| SCHEMBL115626 | 0.79 | ALDH1A1 (0.64) | TSHRHSD17B10CA2CA1BACE1 | |
| SCHEMBL2879838 | 0.79 | TRPA1 (0.52) | TSHRHSD17B10CA2CA1BACE1 | |
| SCHEMBL29433282 | 0.79 | ALDH1A1 (0.64) | TSHRHSD17B10CA2CA1BACE1 | |
| SCHEMBL3692880 | 0.77 | TSHR (0.48) | TSHRHSD17B10CA2CA1BACE1 | |
| SCHEMBL5332433 | 0.77 | LCK (0.67) | TSHRHSD17B10CA2CA1BACE1 | |
| SCHEMBL17548936 | 0.76 | LMNA (0.49) | TSHRHSD17B10CA2CA1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4525304-A | Process for preparing oxazolinoazetidinones | ELI LILLY AND COMPANY (US) | 1985-06-25 | — | — | US | disclosed |
| EP-0109817-A2 | Process for preparing oxazolinoazetidinones | ELI LILLY AND COMPANY (US) | 1984-05-30 | — | — | EP | disclosed |