Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.68 |
| ▸ | GLO1 | Q04760 | 5/20 | 0.60 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332441 | 1.00 | PTGS1 (0.68) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| SCHEMBL570192 | 0.89 | PTGS1 (0.67) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| SCHEMBL14236615 | 0.89 | PTGS1 (0.67) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| SCHEMBL2017370 | 0.89 | PTGS1 (0.67) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| SCHEMBL420277 | 0.89 | PTGS1 (0.67) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| SCHEMBL18009307 | 0.89 | PTGS1 (0.67) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Oxiglutatione SCHEMBL19579378 | 0.88 | PTGS1 (0.73) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Oxiglutatione SCHEMBL4362052 | 0.88 | PTGS1 (0.73) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Oxiglutatione SCHEMBL13561367 | 0.88 | PTGS1 (0.73) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Oxiglutatione SCHEMBL16377441 | 0.88 | PTGS1 (0.73) | PTGS1GSTK1GLO1NOD1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250401-B2 | Therapeutic compositions | ADVANCED THERAPEUTICS AND DIAGNOSTICS, LC (US) | 2007-07-31 | — | — | US | disclosed |
| US-20050130904-A1 | Therapeutic compositions | THIOPHARMA, INC. | 2005-06-16 | — | — | US | disclosed |
| WO-2003053337-A2 | THERAPEUTIC COMPOSITIONS | ADVANCED THERAPEUTICS & DIAGNOSTICS, LC (US) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130904-A1 | Therapeutic compositions | TXNRD3, GLRX3, NR2E3 | PTGS1 458/4885GSTK1 192/4885GLO1 998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.