SCHEMBL2017370

SCHEMBL2017370

CC(=O)SC[C@H](NC(=O)CC[C@H](N)C(=O)O)C(=O)NCC(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 1/20 0.67
▸ GSTK1 Q9Y2Q3 1/20 0.67
▸ GLO1 Q04760 5/20 0.62
▸ NOD1 Q9Y239 5/20 0.44
▸ FOLH1 Q04609 1/20 0.40
▸ GRM8 O00222 1/20 0.38
▸ GRM6 O15303 1/20 0.38
▸ GRIN2D O15399 1/20 0.38
▸ GRIN3B O60391 1/20 0.38
▸ GSR P00390 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ GRIK1 P39086 1/20 0.38
▸ GRM5 P41594 1/20 0.38
▸ GRIA1 P42261 1/20 0.38
▸ GRIA2 P42262 1/20 0.38
▸ GRIA3 P42263 1/20 0.38
▸ SLC1A3 P43003 1/20 0.38
▸ SLC1A2 P43004 1/20 0.38
▸ SLC1A1 P43005 1/20 0.38
▸ GRIA4 P48058 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18009307 1.00 PTGS1 (0.67) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL14236615 1.00 PTGS1 (0.67) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL420277 1.00 PTGS1 (0.67) PTGS1GSTK1GLO1NOD1FOLH1
Hydrochloric Acid SCHEMBL31197175 0.99 PTGS1 (0.65) PTGS1GSTK1GLO1NOD1FOLH1
Sulfuric Acid SCHEMBL31197174 0.95 PTGS1 (0.61) PTGS1GSTK1GLO1NOD1FOLH1
Aspartic Acid SCHEMBL31197177 0.95 PTGS1 (0.61) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL19293445 0.89 PTGS1 (0.65) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL5332446 0.89 PTGS1 (0.68) PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL5332441 0.89 PTGS1 (0.68) PTGS1GSTK1GLO1NOD1FOLH1
S-Methylglutathione SCHEMBL13157330 0.88 PTGS1 (0.71) PTGS1GSTK1GLO1NOD1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260048091-A1 COMPOSITIONS AND METHODS FOR IMPROVING GASTROINTESTINAL HEALTH IN A SUBJECT CROSS III WILLIAM H (US) 2026-02-19 — — US claimed
CN-119909065-A Compositions and methods for treating and reducing alcohol-induced skin flushes 布鲁菲斯特有限责任公司 2025-05-02 — — CN claimed
US-20250073201-A1 COMPOSITIONS AND METHODS FOR TREATING ACUTE ALCOHOL INTAKE NEXT LEVEL HEALTH SCIENCES INC (CA) 2025-03-06 — — US claimed
CN-119015394-A Sulfur-containing compound preparation, and preparation method and application thereof 上海优斐斯生物科技有限公司 2024-11-26 — — CN claimed
EP-4452278-A1 PHARMACEUTICAL COMPOSITION BASED ON GLUTATHIONE THIOESTER AND OLEUROPEIN FOR USE IN THE TREATMENT OF NON-ALCOHOLIC STEATOHEPATITIS Innbiotec Pharma S.R.L. (IT) 2024-10-30 — — EP claimed
US-20240307481-A1 COMPOSITIONS AND METHODS FOR IMPROVING EYE FUNCTION CROSS III WILLIAM H (US) 2024-09-19 — — US claimed
EP-4412625-A1 COMPOSITIONS AND METHODS FOR TREATING ACUTE ALCOHOL INTAKE Next Level Health Sciences Inc. (CA) 2024-08-14 — — EP claimed
CN-117398452-A Composition prepared by eutectic technology and application thereof in improving activity of alcohol dehydrogenase and acetaldehyde dehydrogenase 广东海赫生物医药科技有限公司 2024-01-16 — — CN claimed
WO-2023119167-A1 PHARMACEUTICAL COMPOSITION BASED ON GLUTATHIONE THIOESTER AND OLEUROPEIN FOR USE IN THE TREATMENT OF NON-ALCOHOLIC STEATOHEPATITIS INNBIOTEC PHARMA S.R.L. (IT) 2023-06-29 — — WO claimed
EP-3919054-B1 PHYTOTHERAPEUTIC COMPOSITIONS FOR TOPICAL OR ORAL USE IN ACNE TREATMENT SESTITO FRANCESCO (IT) 2023-06-14 — — EP claimed
EP-2948160-A1 COMPOSITIONS CONTAINING CHONDROITIN SULPHATE, PROTEOLYTIC ENZYMES AND SULPHYDRYL COMPOUNDS FOR IMPROVING THE BIOAVAILABILITY OF CHONDROITIN SULPHATE Gnosis S.p.A. (IT) 2015-12-02 — — EP claimed
WO-2015067708-A1 CRYSTALLINE FORMS OF S-ACETYL GLUTATHIONE, THEIR PREPARATIONS AND USES IN PHARMACEUTICAL AND NUTRACEUTICAL FORMULATIONS GNOSIS S.P.A. (IT) 2015-05-14 — — WO claimed
WO-2014114706-A1 COMPOSITIONS CONTAINING CHONDROITIN SULPHATE, PROTEOLYTIC ENZYMES AND SULPHYDRYL COMPOUNDS FOR IMPROVING THE BIOAVAILABILITY OF CHONDROITIN SULPHATE GNOSIS S.P.A. (IT) 2014-07-31 — — WO claimed
US-20140100283-A1 Method to Increase Absorption and Bioavailability of Oral Glutathione Atlantic Pro Nutrients, Inc. dba XYMOGEN (US) 2014-04-10 — — US claimed
EP-2664330-A1 Composition and medication containing Omega 3 fatty acids and a glucosaminoglucan F. Holzer GmbH (DE) 2013-11-20 — — EP claimed
EP-2444083-A1 Cysteine and food intake Nestec S.A. (CH) 2012-04-25 — — EP claimed
EP-1853292-B1 PHARMACEUTICAL COMPOSITION COMPRISING GLUTATHIONE COMPOUNDS AND BETALAIN FOR THE PREVENTION AND TREATMENT OF CANCER GERNOT TREUSCH (ES) 2008-12-10 — — EP claimed
EP-1154784-B1 THERAPEUTICALLY ACTIVE MIXTURE OF SUBSTANCES CONTAINING S-ACETYLGLUTATHIONE AND ACICLOVIR TREUSCH GERNOT (ES) 2002-10-23 — — EP claimed
EP-1154784-A1 THERAPEUTICALLY ACTIVE MIXTURE OF SUBSTANCES CONTAINING S-ACETYLGLUTATHIONE AND ACICLOVIR Treusch, Gernot (ES) 2001-11-21 — — EP claimed
WO-2000050060-A1 THERAPEUTICALLY ACTIVE MIXTURE OF SUBSTANCES CONTAINING S-ACETYLGLUTATHIONE AND ACICLOVIR TREUSCH GERNOT (ES) 2000-08-31 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048091-A1 COMPOSITIONS AND METHODS FOR IMPROVING GASTROINTESTINAL HEALTH IN A SUBJECT GSS, GLS, GLS2 PTGS1 44/4885GSTK1 20/4885GLO1 74/4885
US-20140100283-A1 Method to Increase Absorption and Bioavailability of Oral Glutathione GSR, GSTP1, GSS PTGS1 172/4885GSTK1 9/4885GLO1 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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