Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TOP1 | P11387 | 2/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29807803 | 0.85 | GAA (0.61) | GAAKDM4EKDM1ANPC1LMNA | |
| SCHEMBL3859948 | 0.85 | GAA (0.61) | GAAKDM4EKDM1ANPC1LMNA | |
| SCHEMBL3928666 | 0.82 | GAA (0.67) | GAAKDM4ENPC1LMNATP53 | |
| SCHEMBL29840068 | 0.82 | GAA (0.67) | GAAKDM4ENPC1LMNATP53 | |
| SCHEMBL11449746 | 0.80 | GPR35 (0.53) | GAANPC1LMNATP53HTT | |
| SCHEMBL15259585 | 0.78 | KDM4E (0.57) | GAAKDM4ELMNATP53HTT | |
| Sulfuric Acid SCHEMBL11242328 | 0.78 | GAA (0.53) | GAAKDM4EKDM1ANPC1LMNA | |
| SCHEMBL7256165 | 0.76 | GAA (0.61) | GAAKDM4EKDM1ALMNATP53 | |
| SCHEMBL5332500 | 0.75 | GAA (0.50) | GAAKDM4EKDM1ALMNATP53 | |
| SCHEMBL7417077 | 0.73 | GAA (0.57) | GAAKDM4ENPC1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007145723-A | UREIDO TROPOLONE DERIVATIVE | RESEARCH FOUNDATION ITSUU LABORATORY | 2007-06-14 | — | — | JP | disclosed |