Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682782 | 0.79 | ALDH1A1 (0.48) | ALDH1A1HSD17B10CYP1A2HPGDMAPT | |
| SCHEMBL5336216 | 0.75 | ALDH1A1 (0.57) | ALDH1A1HSD17B10CYP1A2MAPTGAA | |
| SCHEMBL5332554 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HSD17B10CYP1A2HPGDMAPT | |
| SCHEMBL18092849 | 0.71 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CYP1A2HPGDMAPT | |
| SCHEMBL10069400 | 0.70 | ALDH1A1 (0.48) | ALDH1A1HSD17B10CYP1A2HPGDMAPT | |
| SCHEMBL13947088 | 0.68 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CYP1A2HPGDMAPT | |
| SCHEMBL2310345 | 0.68 | ALDH1A1 (0.48) | ALDH1A1HSD17B10CYP1A2HPGDMAPT | |
| SCHEMBL29858156 | 0.68 | ACACB (0.48) | ALDH1A1HSD17B10CYP1A2HPGDMAPT | |
| SCHEMBL19385989 | 0.68 | ACACB (0.48) | ALDH1A1HSD17B10CYP1A2HPGDMAPT | |
| SCHEMBL5336219 | 0.66 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CYP1A2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797091-A2 | IMIDAZOQUINOLINE COMPOUNDS | Novartis Vaccines and Diagnostics, Inc. (US) | 2007-06-20 | — | — | EP | claimed |
| WO-2006031878-A2 | IMIDAZOQUINOLINE COMPOUNDS | NOVARTIS VACCINES AND DIAGNOSTICS INC. (US) | 2006-03-23 | — | — | WO | claimed |