Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | PRNP | P04156 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332552 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HSD17B10KDM4ECYP1A2MAPT | |
| SCHEMBL4741484 | 0.78 | CYP1A2 (0.47) | ALDH1A1HSD17B10KDM4ECYP1A2MAPT | |
| SCHEMBL18092849 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4ECYP1A2MAPT | |
| SCHEMBL13947088 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HSD17B10KDM4ECYP1A2MAPT | |
| SCHEMBL10069400 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HSD17B10KDM4ECYP1A2MAPT | |
| SCHEMBL3673078 | 0.74 | KDM4E (0.55) | ALDH1A1HSD17B10KDM4ECYP1A2MAPT | |
| SCHEMBL5116887 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HSD17B10CYP1A2MAPTKMT2A | |
| SCHEMBL19385989 | 0.73 | ACACB (0.48) | ALDH1A1HSD17B10KDM4ECYP1A2MAPT | |
| SCHEMBL29858156 | 0.73 | ACACB (0.48) | ALDH1A1HSD17B10KDM4ECYP1A2MAPT | |
| SCHEMBL5332554 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HSD17B10KDM4ECYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480279-A1 | Process for the preparation of pyridineacylals | BASF Aktiengesellschaft (DE) | 1992-04-15 | — | — | EP | disclosed |