Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217416 | 0.64 | TDP1 (0.64) | CHRM2ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6790333 | 0.64 | TDP1 (0.71) | SMN1; SMN2CHRM2MEN1KMT2ATDP1 | |
| SCHEMBL1128426 | 0.63 | PGR (0.56) | LMNASMN1; SMN2CHRM2NPSR1ALDH1A1 | |
| SCHEMBL9220253 | 0.63 | TDP1 (0.76) | CHRM2NPSR1TDP1HPGDL3MBTL1 | |
| SCHEMBL8862878 | 0.62 | TDP1 (0.75) | CHRM2MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL8863154 | 0.62 | TDP1 (0.75) | CHRM2MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL6777483 | 0.62 | TDP1 (0.75) | CHRM2MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL2604742 | 0.62 | TDP1 (0.75) | CHRM2MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL8862728 | 0.62 | TDP1 (0.75) | CHRM2MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL8863094 | 0.62 | TDP1 (0.75) | CHRM2MEN1KMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |