Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 2/20 | 0.45 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14058949 | 0.89 | ACLY (0.53) | ACLYNOTUMIDO1TRIM24NPSR1 | |
| SCHEMBL1179278 | 0.87 | ACLY (0.53) | ACLYNOTUMIDO1TRIM24NPSR1 | |
| SCHEMBL29707967 | 0.87 | ACLY (0.53) | ACLYNOTUMIDO1TRIM24NPSR1 | |
| SCHEMBL15882300 | 0.85 | ACLY (0.61) | ACLYNOTUMIDO1TRIM24XIAP | |
| SCHEMBL29707979 | 0.85 | ACLY (0.61) | ACLYNOTUMIDO1TRIM24XIAP | |
| SCHEMBL10598052 | 0.85 | XIAP (0.60) | ACLYNOTUMIDO1TRIM24XIAP | |
| SCHEMBL13059953 | 0.84 | NOTUM (0.57) | NOTUMMAPK1MEN1KMT2A | |
| SCHEMBL13732806 | 0.84 | NPSR1 (0.62) | ACLYNOTUMIDO1MAPK1NPSR1 | |
| SCHEMBL17545250 | 0.84 | ACLY (0.58) | ACLYNOTUMIDO1TRIM24XIAP | |
| SCHEMBL3497696 | 0.83 | NOTUM (0.52) | NOTUMIDO1TRIM24MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067993-A1 | INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2007-06-14 | — | — | WO | disclosed |