SCHEMBL5332707

SCHEMBL5332707

O=C(O)C1(N2CCCC2)CCCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
CYP2B6 P20813 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
PRCP P42785 1/20 0.33
SLC6A3 Q01959 1/20 0.33
GRIN1 Q05586 1/20 0.33
KCNH2 Q12809 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
HSD11B1 P28845 2/20 0.33
HSD11B2 P80365 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14858388 0.98 ALDH1A1 (0.40) ALDH1A1TP53TSHRCYP2C19GRIN2D
SCHEMBL6138350 0.92 ALDH1A1 (0.39) ALDH1A1TP53TSHRHSD11B1HSD11B2
SCHEMBL14061763 0.92 KDM1A (0.35) ALDH1A1TP53TSHRCYP2C19HSD11B1
Hydrochloric Acid SCHEMBL15194218 0.90 ALDH1A1 (0.38) ALDH1A1TP53TSHRHSD11B1HSD11B2
SCHEMBL234076 0.90 ALDH1A1 (0.41) ALDH1A1TP53TSHRCYP2C19GRIN2D
SCHEMBL25435115 0.90 ALDH1A1 (0.38) ALDH1A1TP53TSHRKDM1AHTT
Hydrochloric Acid SCHEMBL15194272 0.88 ALDH1A1 (0.40) ALDH1A1TP53TSHRCYP2C19GRIN2D
Hydrochloric Acid SCHEMBL15194419 0.88 ALDH1A1 (0.40) ALDH1A1TP53TSHRCYP2C19GRIN2D
SCHEMBL5323192 0.81
SCHEMBL5569331 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007142804-A2 PREPARATION OF COMPLEXING AGENTS AND METAL ION COMPLEXES IN AQUEOUS MEDIA MALLINCKRODT INC. (US) 2007-12-13 WO claimed
WO-2007142804-A2 PREPARATION OF COMPLEXING AGENTS AND METAL ION COMPLEXES IN AQUEOUS MEDIA MALLINCKRODT INC. (US) 2007-12-13 WO disclosed