Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423267 | 0.77 | OPRL1 (0.60) | MEN1CYP2C9KMT2AOPRM1MAPK1 | |
| SCHEMBL1046438 | 0.77 | OPRM1 (0.50) | MEN1CYP2C9KMT2AOPRM1MAPK1 | |
| SCHEMBL8101425 | 0.77 | OPRM1 (0.50) | MEN1CYP2C9KMT2AOPRM1MAPK1 | |
| SCHEMBL2256573 | 0.77 | OPRM1 (0.67) | MEN1CYP2C9KMT2AOPRM1GRIN2D | |
| SCHEMBL2256575 | 0.77 | OPRM1 (0.67) | MEN1CYP2C9KMT2AOPRM1GRIN2D | |
| SCHEMBL9682242 | 0.77 | MEN1 (0.48) | MEN1CYP2C9KMT2AOPRM1MAPK1 | |
| Ammonia Solution, Strong SCHEMBL1158702 | 0.75 | OPRM1 (0.64) | MEN1CYP2C9KMT2AOPRM1GRIN2D | |
| Bromide SCHEMBL28969840 | 0.75 | OPRM1 (0.64) | MEN1CYP2C9KMT2AOPRM1GRIN2D | |
| SCHEMBL8093890 | 0.74 | OPRM1 (0.47) | MEN1CYP2C9KMT2AOPRM1MAPK1 | |
| Bicarbonate SCHEMBL7575333 | 0.73 | MEN1 (0.60) | MEN1CYP2C9KMT2AOPRM1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4014231-B2 | — | — | 2007-11-28 | — | — | JP | claimed |
| EP-1021452-B1 | PROCESS FOR SYNTHESIZING PHOSPHODIESTERS | EPIX MEDICAL INC (US) | 2003-04-02 | — | — | EP | claimed |
| JP-2002511060-A | — | — | 2002-04-09 | — | — | JP | claimed |
| EP-1021452-A1 | PROCESS FOR SYNTHESIZING PHOSPHODIESTERS | Epix Medical, Inc. (US) | 2000-07-26 | — | — | EP | claimed |
| US-5919967-A | Process for synthesizing phosphodiesters | EPIX MEDICAL, INC. (US) | 1999-07-06 | — | — | US | claimed |
| WO-1998046612-A1 | PROCESS FOR SYNTHESIZING PHOSPHODIESTERS | EPIX MEDICAL, INC. (US) | 1998-10-22 | — | — | WO | claimed |
| WO-2007008145-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |