Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.55 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.55 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.55 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429326 | 0.91 | CYP1A2 (0.57) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL27961047 | 0.89 | CYP1A2 (0.68) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL11775774 | 0.89 | CYP1A2 (0.58) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL11778027 | 0.89 | CYP1A2 (0.58) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL10890268 | 0.86 | CYP1A2 (0.64) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL188306 | 0.86 | CYP1A2 (0.64) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL10891708 | 0.86 | CYP1A2 (0.64) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL7665273 | 0.86 | CYP1A2 (0.64) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL29638033 | 0.86 | CYP1A2 (0.64) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL5248985 | 0.86 | CYP1A2 (0.59) | CYP1A2TDP1ALDH1A1TSHRGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005519-B1 | QUICK TEST FOR THE DETERMINATION OF AMMONIA OR OF SUBSTRATES LIBERATING AMMONIA IN REACTIONS | Roche Diagnostics GmbH (DE) | 1983-04-13 | — | — | EP | claimed |
| EP-0005518-B1 | BIS-(2,4-DINITROPHENYL)-METHYL-PYRIDINIUM COMPOUNDS, METHODS FOR THEIR PREPARATION AND THEIR USE AS PH INDICATORS | Roche Diagnostics GmbH (DE) | 1981-09-16 | — | — | EP | claimed |
| US-7803284-B2 | Heat transfer fluids | SOLVAY SOLEXIS S.P.A. (IT) | 2010-09-28 | — | — | US | disclosed |
| US-20100222244-A1 | LUBRICATING COMPOSITIONS BASED ON PERFLUOROPOLYETHERS | SOLVAY SOLEXIS S.P.A. (IT) | 2010-09-02 | — | — | US | disclosed |
| US-20090008596-A1 | HEAT TRANSFER FLUIDS | SOLVAY SOLEXIS S.P.A. (IT) | 2009-01-08 | — | — | US | disclosed |
| US-20080319001-A1 | Cancer Treatment Using Specific 3,6,9-Substituted Acridines | CANCER RESEARCH TECHNOLOGY LTD (GB) | 2008-12-25 | — | — | US | disclosed |
| US-7405296-B2 | Additives of lubricating oils and greases capable to improve their thermal stability; perfluoropolyether; good antirust properties and good stability (high shelf life) to storage at 25 degrees C (without phase separation) | SOLVAY SOLEXIS S.P.A. (IT) | 2008-07-29 | — | — | US | disclosed |
| US-7300930-B2 | Therapeutic acridone and acridine compounds | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2007-11-27 | — | — | US | disclosed |
| US-7300930-B2 | Therapeutic acridone and acridine compounds | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2007-11-27 | — | — | US | disclosed |
| US-7300930-B2 | Therapeutic acridone and acridine compounds | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2007-11-27 | — | — | US | disclosed |
| US-7205311-B2 | Therapeutic acridone and acridine compounds | CANCER RESEARCH TECHNOLOGY LIMITED | 2007-04-17 | — | — | US | disclosed |
| EP-1363888-A2 | THERAPEUTIC ACRIDONE AND ACRIDINE COMPOUNDS | Cancer Research Technology Limited (GB) | 2003-11-26 | — | — | EP | disclosed |
| US-20030207909-A1 | Therapeutic acridone and acridine compounds | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-11-06 | — | — | US | disclosed |
| WO-2002008193-A2 | THERAPEUTIC ACRIDONE AND ACRIDINE COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2002-01-31 | — | — | WO | disclosed |
| EP-0071338-B1 | ELECTROVISCOUS FLUIDS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-08-21 | — | — | EP | disclosed |
| EP-0005518-B1 | BIS-(2,4-DINITROPHENYL)-METHYL-PYRIDINIUM COMPOUNDS, METHODS FOR THEIR PREPARATION AND THEIR USE AS PH INDICATORS | Roche Diagnostics GmbH (DE) | 1981-09-16 | — | — | EP | disclosed |
| US-4245096-A | USEFUL AS PH INDICATORS OF FOR THE DETECTION OF AMMONIA | BOEHRINGER MANNHEIM GMBH (DE) | 1981-01-13 | — | — | US | disclosed |
| EP-0005519-A2 | Quick test for the determination of ammonia or of substrates liberating ammonia in reactions | Roche Diagnostics GmbH (DE) | 1979-11-28 | — | — | EP | disclosed |
| US-3996052-A | Phototropic compounds as acid catalyst in photopolymerizing process | AMERICAN CAN COMPANY (US) | 1976-12-07 | — | — | US | disclosed |
| US-3949143-A | Epoxy resin coatings cured with phototropic aromatic nitro compounds | AMERICAN CAN COMPANY (US) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207909-A1 | Therapeutic acridone and acridine compounds | NAT1, TERT, CCNA1 | CYP1A2 2521/4885TDP1 347/4885ALDH1A1 75/4885 |
| US-20080319001-A1 | Cancer Treatment Using Specific 3,6,9-Substituted Acridines | FOLR1, TP53, FOLR2 | CYP1A2 581/4885TDP1 923/4885ALDH1A1 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.