Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | CDC25A | P30304 | 1/20 | 0.62 |
| ▸ | CDC25B | P30305 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332243 | 0.92 | ALDH1A1 (0.67) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5331484 | 0.91 | ALDH1A1 (0.66) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL6408488 | 0.90 | ALDH1A1 (0.70) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL6404543 | 0.90 | MAPT (0.64) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL14478938 | 0.89 | ALDH1A1 (0.66) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5338687 | 0.87 | MAPT (0.76) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL6403936 | 0.85 | TSHR (0.64) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL18556577 | 0.84 | POLB (0.73) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5334377 | 0.84 | POLB (0.67) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL27175659 | 0.84 | ALDH1A1 (0.62) | MAPTALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |