Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18556577 | 0.94 | POLB (0.73) | POLBLMNAL3MBTL1TSHRMAPK1 | |
| SCHEMBL5333083 | 0.84 | MAPT (0.68) | POLBLMNAL3MBTL1TSHRMAPK1 | |
| SCHEMBL5332243 | 0.84 | ALDH1A1 (0.67) | POLBLMNAL3MBTL1TSHRMAPK1 | |
| SCHEMBL5331484 | 0.83 | ALDH1A1 (0.66) | POLBLMNAL3MBTL1TSHRMAPK1 | |
| SCHEMBL14478938 | 0.83 | ALDH1A1 (0.66) | POLBLMNAL3MBTL1TSHRMAPK1 | |
| SCHEMBL5334648 | 0.82 | MEN1 (0.81) | POLBL3MBTL1TSHRMAPK1ALDH1A1 | |
| SCHEMBL6408488 | 0.82 | ALDH1A1 (0.70) | POLBLMNAL3MBTL1TSHRALDH1A1 | |
| SCHEMBL15983469 | 0.80 | POLB (1.00) | POLBLMNAL3MBTL1TSHRALDH1A1 | |
| SCHEMBL27175659 | 0.80 | ALDH1A1 (0.62) | POLBL3MBTL1TSHRMAPK1ALDH1A1 | |
| SCHEMBL29609536 | 0.80 | POLB (0.68) | POLBLMNAL3MBTL1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |