Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 10/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31201072 | 0.78 | TSHR (0.43) | FDPSGGPS1TSHRSMPD1ALDH1A1 | |
| SCHEMBL4790559 | 0.76 | TSHR (0.39) | FDPSGGPS1TSHRSMPD1ALDH1A1 | |
| SCHEMBL28803556 | 0.76 | FDPS (0.41) | FDPSGGPS1TSHRSMPD1ALDH1A1 | |
| SCHEMBL10602705 | 0.76 | FDPS (0.41) | FDPSGGPS1TSHRSMPD1ALDH1A1 | |
| SCHEMBL17479115 | 0.75 | TSHR (0.48) | FDPSGGPS1TSHRSMPD1ALDH1A1 | |
| SCHEMBL18240327 | 0.75 | TSHR (0.42) | FDPSGGPS1TSHRSMPD1ALDH1A1 | |
| SCHEMBL31648195 | 0.74 | FDPS (0.43) | FDPSGGPS1TSHRSMPD1CES2 | |
| SCHEMBL294887 | 0.74 | ALOX15 (0.52) | FDPSGGPS1TSHR | |
| SCHEMBL2754123 | 0.73 | FDPS (0.39) | FDPSGGPS1TSHRSMPD1ALDH1A1 | |
| SCHEMBL4591909 | 0.73 | ALOX15 (0.50) | FDPSGGPS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1500657-B1 | Substituted pyrazoles as P38 kinase inhibitors | SEARLE LLC (US) | 2007-09-19 | — | — | EP | disclosed |