Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331261 | 0.93 | PTGDR2 (0.42) | PTGDR2HTR6LMNAS1PR1 | |
| SCHEMBL5326882 | 0.92 | HTR6 (0.42) | MAPTPTGDR2POLBHTR6LMNA | |
| SCHEMBL5326854 | 0.90 | HTT (0.44) | MAPTPTGDR2POLBALDH1A1HTR6 | |
| SCHEMBL5332244 | 0.89 | HTR6 (0.47) | MAPTALDH1A1HTR6SMN1; SMN2GAA | |
| SCHEMBL5328962 | 0.86 | PTGDR2 (0.53) | MAPTPTGDR2POLBHTR6LMNA | |
| SCHEMBL5329812 | 0.85 | HTR6 (0.43) | MAPTPTGDR2POLBHTR6LMNA | |
| SCHEMBL5330204 | 0.84 | LMNA (0.51) | MAPTPTGDR2POLBHTR6LMNA | |
| SCHEMBL5325197 | 0.83 | HTR6 (0.52) | MAPTPTGDR2POLBHTR6LMNA | |
| SCHEMBL5330034 | 0.83 | HTR6 (0.41) | HTR6 | |
| SCHEMBL5331999 | 0.82 | HTR6 (0.51) | MAPTPTGDR2POLBHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |