Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5333651 | 0.91 | MAPT (0.46) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL2458130 | 0.87 | NAMPT (0.55) | MAPTSMN1; SMN2MEN1KMT2ATSHR | |
| Trifluoroacetic Acid SCHEMBL2453867 | 0.86 | MAPT (0.53) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL11889641 | 0.85 | MAPT (0.59) | MAPTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL12306050 | 0.79 | MAPT (0.60) | MAPTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL30182423 | 0.78 | MAPT (0.69) | MAPTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL29803251 | 0.78 | MAPT (0.69) | MAPTSMN1; SMN2MEN1KMT2ATSHR | |
| Trifluoroacetic Acid SCHEMBL29803762 | 0.77 | RAB9A (0.56) | MAPTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL24891887 | 0.76 | MAPT (0.64) | MAPTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL11889653 | 0.75 | NPC1 (0.64) | MAPTSMN1; SMN2MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799663-A1 | MODULATORS OF HCV REPLICATION | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006038039-A1 | MODULATORS OF HCV REPLICATION | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2006-04-13 | — | — | WO | disclosed |