SCHEMBL5333698

SCHEMBL5333698

C=C(OCC(C)C)C(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6923985 0.79 TSHR (0.42) TSHRALDH1A1
SCHEMBL8386082 0.74
SCHEMBL12462616 0.73 TSHR (0.37) TSHR
SCHEMBL28105885 0.73 TSHR (0.61) TSHRALDH1A1
SCHEMBL8723924 0.73 TSHR (0.54) TSHRALDH1A1
SCHEMBL891686 0.70
SCHEMBL9498044 0.70
SCHEMBL685935 0.70 PRKCA (0.55) TSHRALDH1A1
SCHEMBL22955111 0.70 ALDH1A1 (0.37) TSHRALDH1A1MAPK1
SCHEMBL27670944 0.70 TSHR (0.46) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011084846-A1 QUATERNARY AMMONIUM SALT PRODRUGS ALKERMES, INC. (US) 2011-07-14 WO disclosed
WO-2007037497-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-04-05 WO disclosed