Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4513857 | 1.00 | GAA (0.35) | GAAL3MBTL1PGRPKMKMT2A | |
| SCHEMBL4505020 | 0.92 | GAA (0.35) | GAAL3MBTL1PGRPKMKMT2A | |
| SCHEMBL5339982 | 0.92 | GAA (0.35) | GAAL3MBTL1PGRPKMKMT2A | |
| SCHEMBL4512824 | 0.91 | PKM (0.36) | GAAL3MBTL1PGRPKMKMT2A | |
| SCHEMBL5334888 | 0.91 | PKM (0.36) | GAAL3MBTL1PGRPKMKMT2A | |
| SCHEMBL4500711 | 0.90 | HSPB1 (0.36) | GAAL3MBTL1PGRSMN1; SMN2MAPT | |
| SCHEMBL5338153 | 0.90 | HSPB1 (0.36) | GAAL3MBTL1PGRSMN1; SMN2MAPT | |
| SCHEMBL14543373 | 0.89 | GAA (0.33) | GAAL3MBTL1PGRPKMKMT2A | |
| SCHEMBL4228448 | 0.83 | GAA (0.34) | GAAL3MBTL1PGRPKMKMT2A | |
| SCHEMBL4512372 | 0.83 | HSPB1 (0.36) | GAAL3MBTL1PKMSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029062-A2 | NOVEL PYRIDINE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |