Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 11/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 2/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333804 | 0.92 | DRD4 (0.40) | KDRTBK1 | |
| SCHEMBL5329735 | 0.92 | TNIK (0.41) | TNIKKDRMERTKTBK1 | |
| SCHEMBL5312320 | 0.91 | KDR (0.49) | KDRGRM2TBK1 | |
| SCHEMBL5310432 | 0.91 | KDR (0.49) | KDRGRM2 | |
| SCHEMBL5334782 | 0.90 | MERTK (0.43) | KDRMERTK | |
| SCHEMBL5311883 | 0.88 | TNIK (0.45) | TNIKKDRGRM2MERTK | |
| SCHEMBL5313556 | 0.85 | MERTK (0.38) | KDRGRM2MERTKCHKA | |
| SCHEMBL5312577 | 0.82 | KDR (0.49) | TNIKKDR | |
| SCHEMBL5314023 | 0.81 | KDR (0.47) | KDRMERTK | |
| SCHEMBL5309711 | 0.80 | GRM2 (0.41) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |