Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 11/20 | 0.43 |
| ▸ | MET | P08581 | 6/20 | 0.43 |
| ▸ | AXL | P30530 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 9/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313556 | 0.92 | MERTK (0.38) | MERTKMETAXLKDR | |
| SCHEMBL5314023 | 0.91 | KDR (0.47) | MERTKMETAXLKDR | |
| SCHEMBL5333764 | 0.90 | TNIK (0.41) | MERTKKDR | |
| SCHEMBL5311867 | 0.89 | MERTK (0.45) | MERTKMETAXL | |
| SCHEMBL5329735 | 0.83 | TNIK (0.41) | MERTKMETAXLKDR | |
| SCHEMBL5333643 | 0.83 | KDR (0.46) | KDR | |
| SCHEMBL5335191 | 0.82 | MAPK8 (0.39) | MERTKMETKDR | |
| SCHEMBL5333804 | 0.82 | DRD4 (0.40) | KDR | |
| SCHEMBL5312320 | 0.81 | KDR (0.49) | KDR | |
| SCHEMBL5310432 | 0.81 | KDR (0.49) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |