Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.45 |
| ▸ | CDK6 | Q00534 | 9/20 | 0.43 |
| ▸ | CCND3 | P30281 | 8/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CDK1 | P06493 | 5/20 | 0.43 |
| ▸ | CDK4 | P11802 | 5/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315552 | 0.91 | BDKRB1 (0.40) | CDK6CCND3CDK4BTKDYRK2 | |
| SCHEMBL5311867 | 0.90 | MERTK (0.45) | TNIKCDK6CCND3CCNE2CDK2 | |
| SCHEMBL5312754 | 0.90 | DYRK2 (0.49) | CDK6CCND3CDK2CDK4CCNA2 | |
| SCHEMBL5333764 | 0.88 | TNIK (0.41) | TNIKGRM2KDRMERTK | |
| SCHEMBL5313507 | 0.81 | DYRK2 (0.45) | CDK6CCND3CDK2CDK1CDK4 | |
| SCHEMBL5315261 | 0.81 | BDKRB1 (0.37) | CDK6CCND3CDK2CDK1CDK4 | |
| SCHEMBL5333804 | 0.80 | DRD4 (0.40) | KDR | |
| SCHEMBL5329735 | 0.80 | TNIK (0.41) | TNIKKDRMERTK | |
| SCHEMBL5312320 | 0.79 | KDR (0.49) | DYRK2GRM2KDR | |
| SCHEMBL5310432 | 0.79 | KDR (0.49) | CDK2CDK1GRM2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |