Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 4/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4497632 | 1.00 | HSPB1 (0.37) | HSPB1TDP2HTR1DHTR1BPKM | |
| SCHEMBL5333522 | 0.92 | HSPB1 (0.36) | HSPB1TDP2PKMGAAL3MBTL1 | |
| SCHEMBL4512372 | 0.92 | HSPB1 (0.36) | HSPB1TDP2PKMGAAL3MBTL1 | |
| SCHEMBL4502235 | 0.91 | HSPB1 (0.36) | HSPB1TDP2HTR1DHTR1BATM | |
| SCHEMBL4517058 | 0.90 | PKM (0.36) | HSPB1HTR1DHTR1BPKMATM | |
| SCHEMBL5337499 | 0.90 | PKM (0.36) | HSPB1HTR1DHTR1BPKMATM | |
| SCHEMBL4232416 | 0.90 | HSPB1 (0.36) | HSPB1TDP2PKMATMGAA | |
| SCHEMBL5329788 | 0.86 | HTR1D (0.35) | HTR1DHTR1B | |
| SCHEMBL4524286 | 0.86 | HTR1D (0.35) | HTR1DHTR1B | |
| SCHEMBL4229234 | 0.84 | HSPB1 (0.35) | HSPB1TDP2PKMGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029062-A2 | NOVEL PYRIDINE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |